| Stage I | T1 – tumor not more than 2 cm in greatest dimension N0 – no regional lymph nodes M0 – no distant metastases |
| Stage IIa | T2 – tumor more than 2 cm but not more than 5 cm in greatest dimension N0 – no regional lymph nodes M0 – no distant metastases |
| Stage IIb | T3 – tumor more than 5 cm in greatest dimension N0 – no regional lymph nodes M0 – no distant metastases |
| Stage IIIa | T1 or T2 N1 – metastasis in regional lymph nodes N1a – inguinal, mesolectal and or internal iliac nodes N1b – external iliac nodes N1c – external iliac, inguinal, mesolectal and or internal iliac nodes M0 – no distant metastases |
| Stage IIIb | T4 – tumor of any size invades adjacent organs (vagina, urethra, bladder); direct invasion of rectal wall, perirectal skin, subcutaneous tissues or sphincter muscles is not considered as T4 N0 – no regional lymph nodes M0 – no distant metastases |
| Stage IIIc | T3 N1 – metastasis in regional lymph nodes M0 – no distant metastases |
| Stage IV | Any T Any N M1 – distant metastases |
8th edition TNM anal cancer staging
