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- Gluten-related immune-mediated enteropathy
- In genetic susceptible individuals
- 1 in 200 people
- Malabsorption, diarrhea, weight loss, steatorrhea, malnutrition, anemia, abdominal pain
- Greater risk of malignancy of small intestine – lymphoma (enteropathy associated T-cell lymphoma) and adenocarcinoma
- Abnormal villous pattern in jejunal biopsy
Imaging
- Barium study
- Dilatation of bowel loops
- Increased intestinal fluid
- Straightened and thickened valvulae conniventes in jejunum
- Numerous mucosal folds in ileum (jejunisation)
- Transient non-obstructive intussusception
- CT
- Bowel dilatation
- Fluid excess
- Bowel wall thickening
- Jejunoileal fold patten reversal
- Transient small bowel intussusception
- Benign mesenteric lymphadenopathy with low attenuation centres
- Mesenteric vascular engorgement
- Complications
- Cavitary mesenteric lymph node syndrome: enlarged, fluid-attenuation mesenteric lymph nodes with thin, peripherally enhancing rims
- Ulcerative jejunoileitis: simulates Crohn disease