Epithelioid hemangioendothelioma

  • Tumor of vascular origin
  • Adult women
  • Consists of epithelioid endothelial cells
  • Occasionally contains punctate calcification
  • Multiple peripheral nodules that coalesce, cause capsular retraction, with compensatory hypertrophy of uninvolved liver segments 
  • Can cause hepatic vein occlusion
  • CT: multiple peripheral heterogeneous areas of low attenuation. Enhancement of rim of nodules with low attenuation halo outside ring of enhancement 
  • US: solid lesions with low reflectivity
  • MRI: low T1, moderate high T2
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Earnest IV, Frank, and C. Daniel Johnson. “Case 96: Hepatic epithelioid hemangioendothelioma.” Radiology 240.1 (2006): 295-298.

Azzam, Ramzi I., Najeeb S. Alshak, and Hong P. Pham. “AIRP best cases in radiologic-pathologic correlation: Hepatic epithelioid hemangioendothelioma.” Radiographics 32.3 (2012): 789-794.