- 5-35 years age
- Arise spontaneously
- Solitary, lobulated, well-defined tumor with central scar
- Punctuate calcification within scar in >50% cases
- Contains fibrotic lamellae and numerous eosinophilic hepatocytes
- Resection when possible
- 5-year survival 60%
- CT: well-defined lobulated, low attenuation mass with even lower attenuation central scar with radial linear components and punctate calcification. Shows non-specific enhancement and delayed enhancement of scar (similar to FNH)
- MR: low signal of scar in both T1 and T2 (FNH scar is T2 bright)
Ichikawa, Tomoaki, et al. “Fibrolamellar hepatocellular carcinoma: pre-and posttherapy evaluation with CT and MR imaging.” Radiology 217.1 (2000): 145-151.
Ganeshan, Dhakshinamoorthy, et al. “Imaging features of fibrolamellar hepatocellular carcinoma.” American Journal of Roentgenology 202.3 (2014): 544-552.