Myxopapillary ependymoma

  • WHO grade I lesion
  • Intradural neoplasm of conus medullaris and filum terminale 
  • Children and young adults
  • Slightly M>F
  • Chronic low back ache worsening in night
  • Slow-growing
  • Usually large when diagnosis is made
  • Mass effect causes scalloping of vertebral body, scoliosis and enlargement of neural foramina 
  • When hemorrhage occurs within lesion, sudden worsening of clinical symptoms with leg weakness and sphincter disturbances
  • Also causes subarachnoid bleeding and siderosis
  • Spontaneous dissemination along craniospinal axis possible, extradural spread also seen post operatively. Post-op radiotherapy helps to reduce recurrence
  • MRI: iso- to hyperintense on T1 (mucin). hyperintense on T2. 
  • Enhances strongly and inhomogeneously 
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Wippold 2nd, F. J., et al. “MR imaging of myxopapillary ependymoma: findings and value to determine extent of tumor and its relation to intraspinal structures.” AJR. American journal of roentgenology 165.5 (1995): 1263-1267.

Frazier, Aletta Ann. “Myxopapillary Ependymoma.” RadioGraphics 39.2 (2019): 467-467.