Myxopapillary ependymoma

• WHO grade I lesion
• Intradural neoplasm of conus medullaris and filum terminale 
• Children and young adults
• Slightly M>F
• Chronic low back ache worsening in night
• Slow-growing
• Usually large when diagnosis is made
• Mass effect causes scalloping of vertebral body, scoliosis and enlargement of neural foramina 
• When hemorrhage occurs within lesion, sudden worsening of clinical symptoms with leg weakness and sphincter disturbances
• Also causes subarachnoid bleeding and siderosis
• Spontaneous dissemination along craniospinal axis possible, extradural spread also seen post operatively. Post-op radiotherapy helps to reduce recurrence

Imaging 

• MRI: iso- to hyperintense on T1 (mucin). hyperintense on T2. 
• Enhances strongly and inhomogeneously 

Read more

Wippold 2nd, F. J., et al. “MR imaging of myxopapillary ependymoma: findings and value to determine extent of tumor and its relation to intraspinal structures.” AJR. American journal of roentgenology 165.5 (1995): 1263-1267.

Frazier, Aletta Ann. “Myxopapillary Ependymoma.” RadioGraphics 39.2 (2019): 467-467.