- Deposition of calcium in renal parenchyma
- Deposition of calcium phosphate and calcium oxalate
- Due to conditions that cause hypercalcemia, hyperphosphatemia and increased excretion of calcium, phosphate or oxalate
- Can be medullary or cortical
Medullary nephrocalcinosis
- Due to metabolic dysfunction
- More common form
- Hyperparathyroidism
- Sarcoidosis
- Medullary sponge kidney disease
- Renal tubular acidosis
- Loop diuretics
- Beta thalassemia
- Inherited tubulopathies
- Oxalosis
- Vitamin-D therapy
Cortical nephrocalcinosis
- Renal cortical nephrocalcinosis
- Glomerulonephritis
- Renal allograft rejection
- Alport syndrome
- Oxalosis
Imaging
- US: hyper echoic renal parenchyma with posterior acoustic shadowing
- X-ray, CT: high-density renal parenchyma in medulla or cortex
Read more
ALON, URI, WILLIAM H. BREWER, and JAMES CM CHAN. “Nephrocalcinosis: detection by ultrasonography.” Pediatrics 71.6 (1983): 970-973.
Schell-Feith, E. A., et al. “Ultrasonographic features of nephrocalcinosis in preterm neonates.” The British journal of radiology 73.875 (2000): 1185-1191.
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