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- Young patients, peak in first decade
- Bilateral lesions diagnostic of neurofibromatosis type 1
- Pilocystic astrocytoma (WHO grade 1) most common. Little or no progression over time
- Visual loss less common in NF-1
Imaging
- Fusiform enlargement of optic nerve
- Expansion of optic canal
- MRI most accurate, iso to hypo on T1, hyper on T2 with variable enhancement