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- Commonest congenital pancreatic abnormality
- Failure of normal fusion of dorsal and ventral anlage
- Dorsal and ventral ducts don’t fuse
- Wirsung (ventral duct) drains head of pancreas via major papilla
- Santorini (dorsal duct) drains body and tail via minor papilla
- Can cause functional stenosis of minor papilla and secondary pancreatitis
- Higher prevalence in patients with recurrent or chronic pancreatitis. Etiology is not the divisum, but rather the genetic mutations associated with divisum causing recurrent inflammation
- MRCP best for visualization of ducts