• Disorder of neuronal organization
  • Occurs after neuronal migration
  • Extent of involvement varies from small, isolated, unilateral areas to large bilateral areas
  • Overconvoluted and fused cortex of normal thickness
  • Sometimes associated with CMV or underlying neurometabolic disorder
  • Broad thickened gyra (mimicking pachygyria) to overconvoluted multiple gyri with irregular outer and inner cortical surfaces
  • May show dystrophic calcification
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Glenn, Orit A., et al. “Malformations of cortical development: diagnostic accuracy of fetal MR imaging.” Radiology 263.3 (2012): 843-855.

Fink, Kathleen R., et al. “Neuroimaging of pediatric central nervous system cytomegalovirus infection.” Radiographics 30.7 (2010): 1779-1796.