Risk stratification in prostate cancer by American Urological Association

Very low riskPSA < 10 ng/ml
Grade group I
Clinical stage T1 – T2a 
< 34% biopsy cores positive
No core >50% involved
PSA density < 0.15 ng/ml/cc
Low riskPSA < 10 ng/ml
Grade group I
Clinical stage T1 –  T2a
Intermediate riskPSA 10-20 ng/ml
Grade group 2 or 3
Clinical stage  T2b-c
Favorable: grade group 1 with PSA 10-20 or grade group 2 with PSA < 10
Unfavorable: grade group 2 with PSA 10-20 or clinical stage T2b-c or grade group 3 with PSA < 20
High riskPSA > 20 ng/ml 
Grade group 4-5
Clinical stage T3 or higher